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J Oleo Sci. 2019 Aug 1;68(8):765-768. doi: 10.5650/jos.ess19054. Epub 2019 Jul 10.

Cycloartenyl Ferulate and β-Sitosteryl Ferulate - Steryl Ferulates of γ-Oryzanol - Suppress Intracellular Reactive Oxygen Species in Cell-based System.

Author information

1
Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine.
2
Tsuno Food Industrial Co., Ltd.

Abstract

γ-Oryzanol is a naturally occurring component of rice bran and consists of various steryl ferulates. The antioxidant activities of γ-oryzanol have mostly been demonstrated in cell-free systems. Therefore, we determined whether steryl ferulate of γ-oryzanol suppress spontaneous intracellular reactive oxygen species (ROS) in cell-based systems. We found that cycloartenyl ferulate and β-sitosteryl ferulate suppressed spontaneous intracellular ROS in a similar way to N-acetylcysteine and α-tocopherol.

KEYWORDS:

cycloartenyl ferulate; intracellular reactive oxygen species; β-sitosteryl ferulate; γ-oryzanol

PMID:
31292340
DOI:
10.5650/jos.ess19054
[Indexed for MEDLINE]
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