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Anaesthesiol Intensive Ther. 2019;51(1):56-63. doi: 10.5603/AIT.2019.0011.

Thrombocytopenia: the most frequent haemostatic disorder in the ICU.

Author information

1
I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny. jan.pluta@wum.edu.pl.
2
I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny.

Abstract

Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.

KEYWORDS:

haemostasis; intensive care unit; thrombocytes; thrombocytopenia

PMID:
31280553
DOI:
10.5603/AIT.2019.0011

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