Format

Send to

Choose Destination
Psychiatry Res Neuroimaging. 2019 Aug 30;290:38-41. doi: 10.1016/j.pscychresns.2019.06.008. Epub 2019 Jul 2.

The resting-brain of obsessive-compulsive disorder.

Author information

1
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal; Clinical Academic Center - Braga, 4710-057 Braga, Portugal. Electronic address: pedromorgado@med.uminho.pt.
2
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal; Clinical Academic Center - Braga, 4710-057 Braga, Portugal.

Abstract

Obsessive-compulsive disorder (OCD) is one of the most debilitating psychiatric conditions, having a dramatic impact on patients' daily living. In this work, we aimed to explore resting-state functional connectivity in OCD patients, using an independent component analysis. Eighty individuals (40 patients and 40 healthy controls) performed a resting state fMRI protocol. OCD patients displayed reduced functional connectivity (FC) in visual and sensorimotor networks. In addition, patients displayed decreased FC between sensory networks and increased FC between default-mode and cerebellar networks.

KEYWORDS:

FMRI; Obsessive–compulsive disorder; Resting-state networks

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center