Short Term Neurobehavioral Outcomes in Late Preterm Neonates Born to Pre-Eclamptic Mothers

Indian Pediatr. 2019 Jun 15;56(6):485-488.

Abstract

Objective: To study the effect of maternal pre-eclampsia on the short-term neurobehavioral outcomes in late preterm neonates using Neurobehavioral Assessment of Preterm Infants (NAPI) score.

Methods: 30 late preterm neonates born to mothers with preeclampsia, and thirty controls born to mothers without pre-eclampsia were enrolled, and followed up to 40 weeks of post-menstrual age. They were evaluated by NAPI score of MDV (Motor development-vigor) and AO (Alertness orientation) at 40 wk.

Results: The mean NAPI score of MDV in cases was 60.1 (9.56) as compared to 70.0 (11.48) in controls (P <0.001). The mean NAPI score of AO in cases was 37.45 (11.04) as compared to 45.6 (13.33) in controls (P=0.006).

Conclusion: Late preterm neonates born to mothers with pre-eclampsia have poor short term neurobehavioral outcomes.

Publication types

  • Observational Study

MeSH terms

  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / diagnosis
  • Infant, Premature, Diseases / etiology*
  • Male
  • Neurodevelopmental Disorders / diagnosis
  • Neurodevelopmental Disorders / etiology*
  • Neuropsychological Tests
  • Pre-Eclampsia*
  • Pregnancy
  • Risk Factors