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J Rheumatol. 1988 Jan;15(1):35-42.

The cost effectiveness of auranofin: results of a randomized clinical trial.

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Institute for Health Research, Harvard School of Public Health, Cambridge, MA.


In a 6-month randomized trial at 14 sites, the cost effectiveness of auranofin (AF) treatment for patients with rheumatoid arthritis was gauged in comparison with placebo. Measures of global health and of impacts on daily life suggest that the benefits of disease modification outweigh adverse effects after 4 and 6 months of treatment (p less than 0.01), with negligible differences between placebo and treated patients after 1 and 2 months. Additional medical costs directly associated with AF treatment amounted to $778/patient annually. Observed differences in less direct medical costs, help received, and earnings were not statistically significant.

[Indexed for MEDLINE]

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