Format

Send to

Choose Destination
Ann Card Anaesth. 2019 Jul-Sep;22(3):254-259. doi: 10.4103/aca.ACA_55_18.

Furosemide: Would it help to improve the lungs as evaluated by sonography and compliance during aortic coarctation surgery.

Author information

1
Department of Anesthesia, Surgical Intensive Care and Pain Management, Faculty of Medicine, Cairo University, Cairo, Egypt.
2
Department of Cardiothoracic Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt.

Abstract

Background:

We evaluated furosemide on attenuating lung injury and/or edema during coarctation repair surgery. We evaluated dynamic lung compliance. We measured the degree of lung edema by means of lung ultrasound (LUS). We recorded the (PaO2/FiO2ratio) as an indicator for oxygenation.

Materials and Methods:

A study was conducted on 56 patients. Patients were divided into two groups: control group (Group C) which did not receive furosemide and furosemide group (Group F) at a dose of 1 mg/kg at induction of anesthesia. Dynamic lung compliance was calculated at induction (Cdyn 1) and at the end of the surgery (Cdyn 2). The (PaO2/FiO2ratio) was calculated at start and end of surgery as (PF 1) and (PF 2), respectively. LUS was performed after induction (LUS 1) and at the end of the surgery. LUS 2 using the 12 regions method plotting the results on scale from 0 to 36. Mechanical ventilation days were recorded.

Results:

Administering furosemide attenuated the lung injury/edema and other pulmonary complications. Furosemide administration improved the dynamic lung compliance in the F Group compared to the C Group. Furthermore, it increased the (PaO2/FiO2ratio) in the F Group compared to the C Group. LUS scale values were lower in the F Group compared to the C Group. There was also less postoperative mechanical ventilation days.

Conclusions:

The use of furosemide was accompanied by improved lung injury/edema profile as indicated by a much less drop in dynamic lung compliance, better oxygenation, a more favorable LUS scale with less parenchymal lung affection.

KEYWORDS:

Coarctation; furosemide; lungs

PMID:
31274485
DOI:
10.4103/aca.ACA_55_18

Supplemental Content

Loading ...
Support Center