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Asian J Androl. 2019 Jul 2. doi: 10.4103/aja.aja_63_19. [Epub ahead of print]

A 30-year retrospective study of rare ectopic seminal tract opening cases.

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Department of Urology, Nanjing BenQ Hospital Affiliated to Nanjing Medical University, Nanjing 210019, China.
Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Department of Urology, Gaogang Hospital of Traditional Chinese Medicine, Taizhou 225321, China.
Fourth Clinical Institute, Nanjing Medical University, Nanjing 211166, China.
Department of Urology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and Nanjing Medical University Affiliated Cancer Hospital, Nanjing 210019, China.


Ectopic seminal tract opening is a rare congenital malformation. Until recently, there has been a lack of comprehensive reporting on the condition. The purpose of this retrospective study is to summarize the experience of diagnosis and treatment of this condition based on 28 clinical practice cases throughout the past 30 years. We conducted auxiliary examinations on such patients including routine tests, imaging examinations, and endoscopy. Among these 28 cases, there were ectopic opening of vas deferens into enlarged prostatic utricles (6 cases); ejaculatory ducts into enlarged prostatic utricles, Müllerian ducts cysts, and urethras (18 cases, 2 cases, and 1 case, respectively); and ectopic opening of the unilateral vas deferens and the contralateral ejaculatory duct into enlarged prostatic utricle (1 case). The size of the enlarged prostatic utricle, the type of ectopic seminal tract opening, and the opening's location effectively assisted in the selection of clinical treatment methods, including transurethral fenestration of the utricle, transurethral cold-knife incision, open operation, laparoscopic operation, and conservative treatment. Satisfactory effect was achieved during follow-up. In conclusion, a definite diagnosis and personalized treatment are especially important for patients with ectopic seminal tract opening.


congenital malformation; ectopic opening; ejaculatory duct; enlarged prostatic utricle; vas deferens

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