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Muscle Nerve. 2019 Sep;60(3):299-304. doi: 10.1002/mus.26627. Epub 2019 Jul 21.

Smoking as risk factor for carpal tunnel syndrome: A birth cohort study.

Author information

1
Department of Hand Surgery, Helsinki University Hospital and University of Helsinki, Finland, P.O. Box 266, FI-00029 HUS, Finland.
2
Center for Life Course Health Research, University of Oulu, Oulu, Finland.
3
Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.

Abstract

BACKGROUND:

Our aim was to determine whether maternal smoking and offspring's own smoking affect the offspring's risk for carpal tunnel syndrome (CTS).

METHOD:

The study sample consisted of the Northern Finland Birth Cohort 1966 (N = 8703). Information on maternal smoking was collected from the participants' mothers. At 31 years, information on smoking, body mass index, socioeconomic status, and long-term illnesses were collected, combined with data of CTS diagnoses from the Care Register for Health Care (1997-2016).

RESULTS:

Maternal smoking was not associated with increased risk of CTS in offspring. Before the age of 31 years, smoking ≤10 pack years (hazard ratio [HR] = 1.54, 95% confidence interval [CI] = 1.11-2.15) and >10 pack years (HR = 1.90; 95% CI = 1.20-3.01) among women, and >10 pack years (HR = 1.89; 95% CI = 1.14-3.12) among men was associated with CTS compared with nonsmokers.

CONCLUSIONS:

In this birth cohort, offsprings' own smoking was associated with CTS; however, maternal smoking was not.

KEYWORDS:

birth cohort; carpal tunnel syndrome; epidemiology; tobacco; upper extremity

PMID:
31271456
DOI:
10.1002/mus.26627

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