Format

Send to

Choose Destination
Clin Infect Dis. 2019 Jul 4. pii: ciz547. doi: 10.1093/cid/ciz547. [Epub ahead of print]

Pandemic uropathogenic fluoroquinolone-resistant Escherichia coli have enhanced ability to persist in the gut and cause bacteriuria in healthy women.

Author information

1
Department of Microbiology, University of Washington School of Medicine, Seattle, WA, USA.
2
ID Genomics, Inc., Seattle, WA, USA.
3
Kaiser Permanente Washington and Kaiser Permanente Washington Research Institute, Seattle, WA, USA.
4
Kaiser Permanente Washington, Seattle, WA, USA.

Abstract

We report that fluoroquinolone resistant Escherichia coli are found in feces of 8.8% healthy adult women, with most bacteria belonging to pandemic multi-drug resistant ST131-H30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented UTI.

KEYWORDS:

Escherichia coli ; Bacteriuria; Fluoroquinolone resistance; Gut microflora; Urinary tract infections

PMID:
31271206
DOI:
10.1093/cid/ciz547

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center