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J Biophotonics. 2019 Jun 28. doi: 10.1002/jbio.201800398. [Epub ahead of print]

Determination of Optical Parameters of the Porcine Eye and Development of a Simulated Model.

Author information

1
Department of Flexible Electronics, Ecole Nationale Supérieure des Mines, Centre Microélectronique de Provence CMP-EMSE, MOC, Gardanne, France.
2
Department of Bioelectronics, Ecole Nationale Supérieure des Mines, Centre Microélectronique de Provence CMP-EMSE, MOC, Gardanne, France.
3
LIIE, Aix Marseille Univ, Marseille, France.
4
CERIMED, Aix Marseille Univ, Marseille, France.

Abstract

The eye is a very sophisticated system of optical elements for the preeminent sense of vision. In recent years, the number of laser surgery to correct the optical aberration such as myopia or astigmatism has significantly increased. Consequently, improving the knowledge related to the interactions of light with the eye is very important in order to enhance the efficiency of the surgery. For this reason, a complete optical characterization of the porcine eye is presented in this study. Kubelka-Munk and Inverse Adding-Doubling methods were applied to spectroscopy measurement to determine the absorption and scattering coefficients. Furthermore, the refractive index has been measured by ellipsometry. The different parameters were obtained for the cornea, lens, vitreous humour, sclera, iris, choroids and eyelid in the visible and infrared region. Thereafter, the results are implemented in a COMSOL Multiphysics® software to create an eye model. This model gives a better understanding of the propagation of light in the eye by adding optical parts such as the iris, the sclera or the ciliary bodies. Two simulations show the propagation of light from the cornea to the retina but also from the sclera to the retina. This last possibility provides a better understanding of light propagation during eye laser surgery such as for e.g. transscleral cyclophotocoagulation. This article is protected by copyright. All rights reserved.

KEYWORDS:

eye simulation model; optical properties; porcine ocular tissues; spectroscopy

PMID:
31251453
DOI:
10.1002/jbio.201800398

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