Send to

Choose Destination
Med Gas Res. 2019 Apr-Jun;9(2):101-105. doi: 10.4103/2045-9912.260652.

Ozone therapy: a potential therapeutic adjunct for improving female reproductive health.

Author information

Department of Biochemistry, Albert Einstein College of Medicine, Bronx; New Hope Fertility Center, New York, NY, USA.
New Hope Fertility Center, New York, NY, USA.
Hocatt USA LLC, Weatherford, TX, USA.


Ozone is emerging as a new adjunct therapeutic agent for female infertility. We here present a review of the literature, to date, pertaining to the effect of ozone therapy on tubal, ovarian, endometrial, and vaginal factors that could potentially affect female fertility. It also presents data pertaining to the relationship of ozone therapy on pelvic adhesion formation. Most data were performed on animals and very few human studies existed in the literature. Results suggested that ozone therapy could have beneficial effect on tubal occlusion, could protect from endometritis and vaginitis, might protect ovaries from ischemia and oocyte loss and finally might lead to less formation of pelvic adhesions. There is a critical need for human studies pertaining to ozone therapy, especially using safe methods of administration, such as transdermally or intravaginally, on female fertility.


adhesions; fallopian tube; infertility; oocyte; ovary; ozone therapy; reproduction; uterus; vagina

Free full text

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd
Loading ...
Support Center