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Kardiologiia. 2019 Jun 5;59(6):26-34. doi: 10.18087/cardio.2019.6.n683.

[Systematic Analysis of the Roles of Trace Elements in the Prevention and Treatment of Chronic Heart Failure].

[Article in Russian]

Author information

1
Federal Research Center for Informatics and Management; Center for Big Data Storage and Analysis, Moscow State University.
2
Moscow State University.
3
N. N. Burdenko National Scientific and Practical Center for Neurosurgery.

Abstract

Systematic analysis of 3 728 publications on the relationship between microelement status and chronic heart failure (CHF) was carried out. Three main areas of research have been identified: 1) magnesium, electrolytes and CHF; 2) the transcriptional and antioxidant effects of zinc, selenium, copper; 3) iron-deficiency anemia and CHF. In this paper, we consider a complex of relationships between the magnesium insufficiency and CHF, the effect of magnesium on vascular tone, mitochondria, heart rhythm and the susceptibility of cardiomyocytes to adrenergic stimulation. Using magnesium orotate for the treatment of CHF is a feasible approach to compensate magnesium insufficiency in patients with CHF.

PMID:
31242838
DOI:
10.18087/cardio.2019.6.n683
[Indexed for MEDLINE]

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