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Indian J Ophthalmol. 2019 Jul;67(7):1240-1245. doi: 10.4103/ijo.IJO_1553_18.

Solitary orbital myofibroma in a child: A rare case report with literature review.

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Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, Bhubaneswar, Odisha, India.
Kanupriya Dalmia Ophthalmic Pathology Laboratory, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.


Myofibroma is a rare benign mesenchymal tumor of uncertain histogenesis. A six-year-old boy presented with a unilateral lower eyelid mass of six weeks' duration. MRI revealed a circumscribed mass in the inferolateral orbit with bony erosion. A systemic examination was unremarkable. Excision with histopathology revealed a partially infiltrative spindle cell tumor with bland nuclear morphology expressing smooth muscle actin and muscle-specific actin, compatible with myofibroma. Solitary myofibroma is a rare childhood orbital tumor and may clinico-radiologically closely mimic a malignancy. Histopathology and immunohistochemistry can help reach a definitive diagnosis. Systemic evaluation and close follow up are crucial in such cases.


Benign; bone erosion; children; myofibromatosis; orbital myofibroma

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