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Iran J Public Health. 2019 Mar;48(3):410-420.

Effect of Selenium on Thyroid Disorders: Scientometric Analysis.

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Department of Oculofacial, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Vice Chancellery of Research and Technology, Isfahan University of Medical Sciences, Isfahan, Iran.
International Virtual Ophthalmic Research Center, Tehran, Iran.
Department of Pathology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Immunoregulation Research Center, Shahed University, Tehran, Iran.
Department of Ophthalmology, Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.



Association of Selenium (Se) deficiency, an essential trace element, has been found with human diseases. Identifying literature trends on the effects of Se on the thyroid may guide in planning future studies.


A literature search was conducted using the Web of Science database to identify studies on Se and the thyroid published over the 20 years duration (1995-Dec 2014). Scientometric indices were used to draw field maps. The scientific processes, structure, evidence history, and international collaborations were included in the map. The most influential authors, journals, institutions, and countries were also examined.


Our search identified 184 research and review papers. The number of scientific studies on Se and the thyroid has been irregular, but interest in this topic has increased in recent years. The highest number of studies was published in 2014 (16 papers) and overall growth factor of publication was 3.78. Overall, 744 authors from 282 institutions in 43 countries published in this field. The author J. Kohrle (828 citations, 14 publications), and German scientists (1272 citations, 30 publications) were most influential.


This study reveals the interrelationships between different publications on the effects of Se on the thyroid. Leading scientific issues and their extent of impact were successfully determined by examining citations. The results of systematic citations and mapping fields can be used to assist in policy and management contexts.


Field maps; International collaborations; Scientometric analysis; Selenium; Thyroid disorders


Conflict of interest statement

Conflict of interest The authors declare that there is no conflict of interests.

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