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Neurobiol Dis. 2019 Oct;130:104504. doi: 10.1016/j.nbd.2019.104504. Epub 2019 Jun 16.

A brief history of antibody-based therapy.

Author information

1
Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada; Centre de Recherche du CHU de Québec, Axe Neuroscience, T2-50, 2705, Boulevard Laurier, Québec, QC G1V 4G2, Canada. Electronic address: melanie-jeanne.alpaugh.1@ulaval.ca.
2
Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada; Centre de Recherche du CHU de Québec, Axe Neuroscience, T2-50, 2705, Boulevard Laurier, Québec, QC G1V 4G2, Canada. Electronic address: francesca.cicchetti@crchudequebec.ulaval.ca.

Abstract

Active and passive immunization have been used to treat human disease for hundreds of years and improvements in technology and knowledge is only increasing the number of therapeutic applications. The current and future use of immunization to treat neurodegenerative diseases are briefly described herein to serve as an introduction to this special issue.

KEYWORDS:

Active immunization; Alzheimer's disease; Cancer; Huntington's disease; Infectious diseases; Parkinson's disease; Passive immunization; Vaccination

PMID:
31216439
DOI:
10.1016/j.nbd.2019.104504

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