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Dev Cell. 2019 Jun 17;49(6):819-820. doi: 10.1016/j.devcel.2019.05.042.

Anillin Puts RhoA in Touch with PIP2.

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1
Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA. Electronic address: emunro@uchicago.edu.

Abstract

In this issue of Developmental Cell, Budnar and colleagues report how the scaffolding protein anillin uses cycles of transient binding interactions to enhance the residence time and signaling output of active RhoA to control actomyosin contractility at epithelial junctions and during cell division.

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