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Dermatol Surg. 2019 Jun 17. doi: 10.1097/DSS.0000000000001965. [Epub ahead of print]

Platelet-Rich Plasma and Its Utilities in Alopecia: A Systematic Review.

Author information

1
Department of Dermatology, University of Michigan, Ann Arbor, Michigan.
2
Department of Dermatology, Johns Hopkins University, Baltimore, Maryland.

Abstract

BACKGROUND:

The use of platelet-rich plasma is becoming more prevalent in the field of dermatology. Variable preparation techniques and treatment methods have been described with reported success in alopecia.

OBJECTIVE:

To consolidate the available evidence of platelet-rich plasma and its utility in the treatment of alopecia for the practicing dermatologist.

METHODS:

Evaluating the available evidence up to May 31, 2018, a search was conducted in the PubMed database for "platelet rich plasma" or "platelet releasate" or "platelet gel" or "PRP" and "dermatology" or "skin" or "hair" or "cutaneous."

RESULTS:

Nineteen articles met the inclusion criteria for analysis including 3 alopecia areata studies with a total of 71 patients and 16 androgenetic alopecia studies with a total of 389 patients. Although the heterogeneity of the studies prevented direct comparisons and subsequent statistical analysis, the majority demonstrated that platelet-rich plasma produced successful hair growth in androgenetic alopecia and alopecia areata.

CONCLUSION:

This review advocates for the use of platelet-rich plasma in 3 to 4 monthly sessions for the treatment of alopecia. Future studies should include a detailed description of the platelet-rich plasma isolation process to allow for comparison among studies, provide reproducibility, and generate a standardized treatment protocol.

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