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Leg Med (Tokyo). 2019 Jul;39:45-48. doi: 10.1016/j.legalmed.2019.06.005. Epub 2019 Jun 11.

Genetic characterization of 21 autosomal STR loci of Goldeneye™ DNA ID 22NC Kit in Chinese She group.

Author information

1
Department of Forensic Science, Medical School of Soochow University, Suzhou 215123, PR China; Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China.
2
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China; Department of Forensic Medicine, School of Basic Medical Science, Wenzhou Medical University, Wenzhou 325035, PR China.
3
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China; Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, PR China.
4
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China; College of Medicine and Forensics, Xi'an Jiaotong University Health Science Center, Xi'an 710061, PR China.
5
Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China. Electronic address: zhangsh@ssfjd.cn.
6
Department of Forensic Science, Medical School of Soochow University, Suzhou 215123, PR China; Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, PR China. Electronic address: lichengtaohla@163.com.

Abstract

Genetic polymorphism of 21 autosomal STR loci included in Goldeneye™ DNA ID 22NC Kit (D19S253, D6S477, D22GATA198B05, D15S659, D8S1132, D3S1358, D3S3045, D14S608, D17S1290, D3S1744, D2S411, D18S535, D13S325, D7S1517, D10S1435, D11S2368, D4S2366, D1S1656, D7S3048, D10S1248 and D5S2500) was studied in 297 unrelated She individuals. Allele frequencies and forensic efficiency parameters such as, observed and expected heterozygosity (Ho & He), matching probability (MP), power of discrimination (PD), polymorphism information content (PIC), power of exclusion (PE), typical paternity index (TPI) was calculated for the loci. The combined PD and PE for all 21 STR loci were calculated to be 0.999999999999999999999999324094 and 0.999999996182425, respectively. The dataset indicated the usefulness of these loci in personal identification, parentage testing and complex kinship analysis in She population. The MDS plots and neighbor-joining tree were constructed based on pair-wise Nei's genetic distance by comparing allele frequency data for the 21 loci with ten other populations. The analysis showed that She population lies closer to a clade consisting Southern Han, Hainan Han and Li populations.

KEYWORDS:

Genetic data; She population; Short tandem repeat (STR)

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