Send to

Choose Destination
Natl J Maxillofac Surg. 2019 Jan-Jun;10(1):27-32. doi: 10.4103/njms.NJMS_15_18.

Assessment and correlation between functional and histological staging of oral submucous fibrosis: A clinicohistopathologic study.

Author information

Department of Oral Medicine and Radiology, RR Dental College and Hospital, Umarda, Udaipur, Rajasthan, India.
Department of Oral Medicine and Radiology, VS Dental College and Hospital, Bengaluru, Karnataka, India.
Department of Oral and Maxillofacial Surgery, AIIMS, New Delhi, India.
Department of Prosthodontics and Implantology, RR Dental College and Hospital, Umarda, Udaipur, Rajasthan, India.
Department of Conservative Dentistry and Endodontics, Darshan Dental College and Hospital, Udaipur, Rajasthan, India.
Department of Dentistry, East Point College of Medical Science and Research Centre, Bengaluru, Karnataka, India.


Background and Objective:

Oral submucous fibrosis (OSMF) is a precancerous condition. It is widespread in the Asian subcontinent, with India bearing most of the burden. It is characterized by mucosal rigidity of varying intensity due to the fibroelastic changes of the juxta epithelial layer, resulting in a progressive inability to open the mouth. Early recognition with accurate staging of the disease and appropriate treatment planning is of utmost importance to prevent the malignant transformation and to improve the quality of life of the patient. In the present study, an attempt is made to clinically evaluate the condition and correlate it with the histopathological findings according to standard criteria.

Materials and Methods:

A hospital-based study was conducted on sixty OSMF patients. Detailed history was recorded, and functional staging was given depending on mouth opening. Punch biopsy was performed, and histological stages were given based on standard criteria. The data so received were mathematically evaluated to determine whether any correlation exists between the stages using Chi-square test.


The sixty patients were in the age range of 16-50 years. Male-to-female ratio was that of 97:3. The statistical analysis using Chi-square test showed statistically significant association (P < 0.001) between the functional and histologic stages.


There is a definite correlation between functional and histological stages of OSMF which suggests that clinically advanced OSMF has extensive fibrosis histologically.


Functional staging; histological staging; oral submucous fibrosis

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center