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Obstet Gynecol. 1987 Dec;70(6):840-5.

A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman.

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  • 1Dulwich Menopause Clinic, King's College Hospital School of Medicine and Dentistry, London, England.


The skin collagen content, skin thickness, metacarpal index, and forearm bone mineral content in postmenopausal women showed a similar decline of between 1-2% per year after the menopause. All four parameters showed a decline that was significant when compared with the years from the menopause. Significant correlations between all four parameters suggest that a similar pathology causes the decrease in bone mass and skin thickness--a decline in the connective tissue element that is common to both bone and skin.

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