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J Glob Infect Dis. 2019 Apr-Jun;11(2):80-82. doi: 10.4103/jgid.jgid_10_16.

The Largest American Study Comparing Transient Elastography and the Aminotransferase-to-platelet Ratio Index Score, Two Noninvasive Tests for Liver Fibrosis Staging in HIV/HCV Coinfected Patients.

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Department of Infectious Diseases, Seton Hall University, NJ, USA.
Department of Infectious Diseases, St. Michael's Medical Center, NJ, USA.



Elastography has become the standard of care of diagnostic approaches for liver disease, particularly when dealing with hepatitis C. There areno studies in the inner-city populations of Newark, New Jersey, that describe the comparison of noninvasive markers, such as FibroScan andaminotransferase-to-platelet ratio index (APRI) scoring.


Using a chart review method, we used a case-control study method of gathering and analyzing the data, using P < or = 0.05 as a significant variable.


The outcome of this study indicates that the FibroScan may be a better marker than the APRI score for the staging of liver disease when a patient has hepatitis B or C with or without HIV/AIDS.


This may be a benchmark study to further enhance our understanging of the utility of the fibroscan.


Aminotransferase-to-platelet ratio index; FibroScan; HIV; elastography; hepatitis C

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