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J Glob Infect Dis. 2019 Apr-Jun;11(2):80-82. doi: 10.4103/jgid.jgid_10_16.

The Largest American Study Comparing Transient Elastography and the Aminotransferase-to-platelet Ratio Index Score, Two Noninvasive Tests for Liver Fibrosis Staging in HIV/HCV Coinfected Patients.

Author information

1
Department of Infectious Diseases, Seton Hall University, NJ, USA.
2
Department of Infectious Diseases, St. Michael's Medical Center, NJ, USA.

Abstract

Objective:

Elastography has become the standard of care of diagnostic approaches for liver disease, particularly when dealing with hepatitis C. There areno studies in the inner-city populations of Newark, New Jersey, that describe the comparison of noninvasive markers, such as FibroScan andaminotransferase-to-platelet ratio index (APRI) scoring.

Methods:

Using a chart review method, we used a case-control study method of gathering and analyzing the data, using P < or = 0.05 as a significant variable.

Results:

The outcome of this study indicates that the FibroScan may be a better marker than the APRI score for the staging of liver disease when a patient has hepatitis B or C with or without HIV/AIDS.

Conclusions:

This may be a benchmark study to further enhance our understanging of the utility of the fibroscan.

KEYWORDS:

Aminotransferase-to-platelet ratio index; FibroScan; HIV; elastography; hepatitis C

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