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Anesth Essays Res. 2019 Apr-Jun;13(2):389-394. doi: 10.4103/aer.AER_37_19.

A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery.

Author information

1
Department of Anaesthesiology, Kodagu Institute of Medical Sciences, Kodagu, Karnataka, India.
2
Department of Anaesthesiology, Sakra World Hospital, Bangalore, Karnataka, India.
3
Department of Anaesthesiology, M.S. Ramaiah Medical College, Bangalore, Karnataka, India.
4
Department of Anaesthesiology, BGS Global Institute of Medical Sciences, Bangalore, Karnataka, India.

Abstract

Context:

Adjuvants to bupivacaine for single shot caudal block in children.

Aims:

This study entitled was conducted to compare the effects of addition of tramadol to bupivacaine over addition of clonidine to bupivacaine as a single shot caudal block in children.

Settings and Design:

Sixty children of ASA grade I and II in the age group of 2-12 years coming for various infra-umbilical surgeries were included.

Materials and Methods:

They were divided into two groups of 30 each. Group BC received caudal bupivacaine 0.25% 0.5ml/kg with clonidine 2 mcg/kg Group BT received caudal bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg. The main parameters studied were hemodynamic changes, duration of post-operative analgesia and incidence of adverse effects.

Statistical Analysis Used:

The results of continuous variables are given as mean ± SD and proportion as percentage. The difference between the two groups was assessed by student's - t test and chi-square test.

Results:

The mean duration of post-operative analgesia in group BT was statistically significant (P <0.001), reducing the requirement of analgesics in group BT. There was no difference in sedation score, nausea, vomiting, urinary retention.

Conclusions:

The present study demonstrated that caudal administration of bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg resulted in superior analgesia with longer duration of action and reduced requirement of analgesics in first 24 hours postoperatively when compared with 0.25% bupivacaine 0.5 ml/kg with clonidine 2 mcg/kg.

KEYWORDS:

Adjuvants; caudal space; epidural space; post operative analgesia; sedation

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