Format

Send to

Choose Destination
Dokl Biol Sci. 2019 Mar;485(1):30-32. doi: 10.1134/S0012496619020042. Epub 2019 Jun 13.

Physical Fatigue and Morphofunctional State of the Myocardium in Experimental Chronic Stress.

Author information

1
Research Institute of Human Morphology, 117418, Moscow, Russia. marivladiko@mail.ru.
2
South Ural State University, 454080, Chelyabinsk, Russia.
3
Institute of Immunology and Physiology, 620039, Yekaterinburg, Russia.
4
Yeltsin Federal University, 620002, Yekaterinburg, Ural, Russia.
5
Vitebsk State Medical University, 210009, Vitebsk, Belarus.
6
Institute of General Pathology and Pathophysiology, 125315, Moscow, Russia.
7
University of North Texas Health Science Center, 76107, Fort Worth, United States of America.

Abstract

The relationship between the development of skeletal muscle fatigue of a specific type in male Wistar rats and morphofunctional alterations in the myocardium in the posttraumatic stress disorder (PTSD) model has been investigated for the first time. The aggravation of oxidative stress in the cardiomyocytes and the related transformation of the cell structural components and the depletion of energy reserves in PTSD has been identified as one of the main factors that accelerate the onset of musculoskeletal fatigue.

PMID:
31197589
DOI:
10.1134/S0012496619020042
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center