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Cell Host Microbe. 2019 Jun 12;25(6):769-770. doi: 10.1016/j.chom.2019.05.011.

Seeing Is Believing: Vitamin A Promotes Skin Health through a Host-Derived Antibiotic.

Author information

1
Department of Dermatology, University-Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: jschroeder@dermatology.uni-kiel.de.

Abstract

In this issue of Cell Host & Microbe, Harris et al. (2019) show that members of the resistin-like molecule (RELM) family are bactericidal, antimicrobial peptides that promote skin defenses in a vitamin-A-dependent manner. Administration of vitamin A analogs triggers RELM, which improves host resistance against skin pathogens in mice.

PMID:
31194936
DOI:
10.1016/j.chom.2019.05.011
[Indexed for MEDLINE]

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