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Exp Cell Res. 1987 Nov;173(1):267-73.

Galactosyltransferase and sialyltransferase are located in different subcellular compartments in HeLa cells.

Author information

1
University of Basel, Switzerland.

Abstract

Galactosyl- and sialyltransferase have been localized by double immunofluorescence labeling in HeLa cells. Galactosyltransferase was found in a compact juxtanuclear structure previously shown to represent the Golgi apparatus (J. Roth and E.G. Berger (1982) J. Cell Biol. 93, 223-9), whereas sialyltransferase was localized to vesicles spread over the whole cytoplasm. These findings indicate different compartments for both transferases and support a model of subcompartmentation of glycosylation steps along the secretory pathway.

PMID:
3119357
DOI:
10.1016/0014-4827(87)90352-1
[Indexed for MEDLINE]

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