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J Bone Jt Infect. 2019 Apr 20;4(3):111-114. doi: 10.7150/jbji.34484. eCollection 2019.

Treatment of a Recurrent Periprosthetic Joint Infection with an Intramedullary Knee Arthrodesis System with Low-Amount Metallic Silver Coating.

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Department of Trauma Surgery, Regensburg University Medical Center, Germany.
Department of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen-Marburg, Campus Giessen, Germany.


We present a case of a recurrent periprosthetic knee infection treated with an intramedullary arthrodesis system coated with low amounts of metallic silver. After a follow-up of 26 months, the patient remained infection free and no silver-related complications were detected. Silver serum concentrations remained below the detection limit of 2 ppb.


Staphylococcus; arthrodesis; knee; periprosthetic joint infection; silver

Conflict of interest statement

Competing Interests: VA is a member of the Supervisory Board of Bio-Gate AG, Nürnberg, Germany. No author has received any grants from the involved companies (Bio-Gate AG, Nürnberg (silver coating technology) or Merete GmbH, Berlin, Germany (knee arthrodesis device)).

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