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Chem Soc Rev. 2019 Jul 29;48(15):4019-4035. doi: 10.1039/c8cs00856f.

Non-spherical polymersomes: formation and characterization.

Author information

1
School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia. chinkenwong@gmail.com m.stenzel@unsw.edu.au p.thordarson@unsw.edu.au.

Abstract

Polymersomes are self-assembled hollow membrane sacs that are not only able to encapsulate hydrophobic and/or hydrophilic molecules, but also possess exceptional chemical and physical stability, structural versatility, and surface modifiability. For the above reasons, polymersomes have in recent years emerged as a powerful tool for a wide range of applications in the fields of biomimicry and drug delivery. The full potential of polymersomes, however, has yet to be harnessed due to a lack of appreciation of existing shape control methods. This very much contrasts the field of inorganic nanoparticle synthesis where non-spherical hollow metal nanoparticles are routinely prepared and used. Here, we summarize recent efforts over the past decade to study the morphological transformation of conventionally spherical polymersomes into non-spherical polymersomes.

PMID:
31187792
DOI:
10.1039/c8cs00856f

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