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Obes Surg. 2019 Jun 10. doi: 10.1007/s11695-019-03983-5. [Epub ahead of print]

Laparoscopic Sleeve Gastrectomy in Sickle Cell Disease: a Case Series.

Author information

1
Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
2
Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, 840 S Wood St, 820-E-CSB, Chicago, IL, 60612, USA.
3
Center for Pharmacoepidemiology and Pharmacoeconomic Research, University of Illinois at Chicago, Chicago, IL, USA.
4
Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, 840 S Wood St, 820-E-CSB, Chicago, IL, 60612, USA. ssaraf@uic.edu.

Abstract

With improved care, the number of sickle cell patients with obesity is increasing. The experience with bariatric surgery in this patient population is limited. We describe four adult patients with mild sickling genotypes who underwent laparoscopic sleeve gastrectomy. The patients achieved marked weight loss with percentage of excess weight loss ranging from 56 to 68%. The surgery was associated with decreases in white blood cell counts and lower random glucose concentrations. No short-term or long-term complications related to the surgery were observed. Our report supports bariatric surgery as a feasible weight-loss option in this patient population.

KEYWORDS:

Bariatric surgery; Glucose; Sickle cell disease; White blood cell

PMID:
31183783
DOI:
10.1007/s11695-019-03983-5

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