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Clin Exp Immunol. 2019 Jun 8. doi: 10.1111/cei.13338. [Epub ahead of print]

Regulatory T cells: exploring mechanisms for future therapies.

Author information

1
Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada, H3A 2B4.
2
Program in Infectious Diseases and Immunology in Global Health, the Research Institute of the McGill University Health Centre, Montréal, Québec, Canada, H4A 3J1.
3
Centre of Excellence in Translational Immunology (CETI), Montréal, Québec, Canada, H4A 3J1.

Abstract

In this two-part Review Series for Clinical & Experimental Immunology, we have invited experts in their fields to contribute review articles on the recent progress in understanding the genetic basis of regulatory T cell functional development, their role in ensuring tolerance in health, the underlying mechanisms underlying their dysfunction in diseased states, and their use in cellular therapies for the treatment of a host inflammatory conditions in humans. This article is protected by copyright. All rights reserved.

PMID:
31177531
DOI:
10.1111/cei.13338

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