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Sci Rep. 2019 Jun 6;9(1):8321. doi: 10.1038/s41598-019-38969-x.

Model of a Support Vector Machine to Assess the Functional Cure for Surgery of Intermittent Exotropia.

Liu Y1,2, Liu C3, Zhang W4,5,6, Chen X4,5,6, Zhao K7,8,9.

Author information

1
Baodi Clinical College, Tianjin Medical University, 8 Guangchuan Road, Tianjin, 301800, China.
2
Tianjin Baodi Hospital, 8 Guangchuan Road, Tianjin, 301800, China.
3
State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering, Hohai University, Nanjing, 210098, China.
4
Tianjin Eye Hospital, 4 Gansu Road, Tianjin, 300020, China.
5
Tianjin Key Laboratory of Ophthalmology and Visual Science, 4 Gansu Road, Tianjin, 300020, China.
6
Tianjin Eye Institute, 4 Gansu Road, Tianjin, 300020, China.
7
Tianjin Eye Hospital, 4 Gansu Road, Tianjin, 300020, China. zkx4260@vip.163.com.
8
Tianjin Key Laboratory of Ophthalmology and Visual Science, 4 Gansu Road, Tianjin, 300020, China. zkx4260@vip.163.com.
9
Tianjin Eye Institute, 4 Gansu Road, Tianjin, 300020, China. zkx4260@vip.163.com.

Abstract

In this paper the optimum timing for the postoperative functional cure of basic intermittent exotropia is explored based on support vector machine (SVM). One hundred and thirty-two patients were recruited in this prospective cross-sectional study with 6 months of follow-up. Examinations included angle of deviation, central and peripheral fusion, controllability, and near and distance stereopsis. Influencing factors of postoperative alignment and stereopsis were analyzed with a chi-squared test and univariate and multivariate logistic regression analyses. At 6 months post-operation, there were 84 successful procedures for the angle of deviation, with 4 overcorrections and 44 undercorrections. The success rate was 63.6%. The angle of deviation on postoperative day 1 was the only significant associated factor. One hundred and thirty patients had normal near stereoacuity, 60 had normal distance stereoacuity according to a Functional Visual Analyzer assessment, and 108 had normal stereoacuity as assessed by the Frisby Davis Distance (FD2) stereotest. The age of onset and preoperative distance stereoacuity with FD2 were the influencing factors of postoperative distance stereopsis restoration. The accuracy of this method of SVM was 82.1%. The angle of deviation for distance on postoperative day 1 was the only significant factor that correlated with alignment at 6 months post-operation, and the model of SVM was useful to determine the optimal time of the postoperative functional cure.

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