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Indian J Dent Res. 2019 Mar-Apr;30(2):318-321. doi: 10.4103/ijdr.IJDR_282_19.

Transzygomatic, transcondylar excision of the sarcoma of infratemporal fossa.

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Department of Oral and Maxillofacial Surgery, Balaji Dental and Craniofacial Hospital, Chennai, Tamil Nadu, India.


Malignant peripheral nerve sheath tumor (MPNST) is a rare pathologic lesion in a patient with solitary neurofibroma. A 32-year-old man presented with a firm and slightly tender mass in the right infratemporal region involving the right preauricular and temporomandibular joint area. The patient has a history of removal of a solitary neurofibroma 22 years back in the same region. The lesion had enlarged rapidly over the past 3 months, and a spindle cell lesion was diagnosed through a superficial incisional biopsy. Surgical removal of the lesion using modified preauricular transzygomatic approach was done. Histopathologically, it was diagnosed as an MPNST.


Infratemporal fossa; malignant peripheral nerve sheath tumor; neurofibroma; surgical removal

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