[The clinical effects of methylprednisolone combined with vestibular rehabilitation and methylprednisolone in the treatment of vestibular neuritis]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun;33(6):493-497. doi: 10.13201/j.issn.1001-1781.2019.06.004.
[Article in Chinese]

Abstract

Objective:To explore the clinical effect of vestibular rehabilitation on vestibular neuritis. Method:Fifty patients with vestibular neuritis (VN) were randomly divided into study group (n=26) and control group (n=24). The patient in study group received methylprednisolone treatment and peripheral vestibular rehabilitation therapy, while that in the control group received methylprednisolone only. Spontaneous nystagmus (SN), caloric test (CP), directional preponderance (DP),vestibular muscle evoked potential (VEMP) were comparative for study group and control group at admission, 1 month after treatment, and 3 months after treatment. Result:①There was no significant difference in the balance between the two groups. ②After 1 month treatment, the directional preponderance of DP decreased (P<0.01) in the study group(21.09±16.90)% compared with the control group(41.11±24.03)%, VEMP extraction rate increased (P<0.05) in the study group compared with the control group, dynamic balance score of the study group (70.77±16.15) increased (P<0.05) compared with the control group (53.83±26.76). ③After 3 months, canal paresis CP of the study group (33.26±20.01)% decreased (P<0.05) compared with the control group (50.07±25.42)%, DP of the study group (8.63±5.65)% decreased (P<0.01) compared with the control group (17.98±8.84)%, and the comprehensive dynamic balance score of the study group (81.58±3.67) increased (P<0.01) compared with the control group (62.50±29.24). Conclusion:Peripheral vestibular rehabilitation can accelerate vestibular compensation and is an effective treatment for vestibular neurons.

目的:探讨前庭康复治疗前庭神经炎的临床效果。 方法:将50例前庭神经炎患者随机分为研究组(26例)与对照组(24例)。研究组给予甲泼尼龙治疗和外周性前庭康复训练,对照组只给予甲泼尼龙治疗,对比2组入院时、治疗1个月、3个月后的自发性眼震、半规管轻瘫(CP)、优势偏向(DP)、前庭肌源诱发电位(VEMP)、动态平衡综合得分等各项指标的变化情况。 结果:①两组均衡性比较差异无统计学意义。②治疗1个月后,研究组的DP[(21.09±16.90)%]较对照组[(41.11±24.03)%]降低(P<0.01);VEMP未引出率较对照组降低(P<0.05);动态平衡综合得分[(70.77±16.15)分]较对照组[(53.83±26.76)分]增高(P<0.05)。③治疗3个月后,研究组的CP[(33.26±20.01)%]较对照组[(50.07±25.42)%]降低(P<0.05);DP[(8.63±5.65)%]较对照组[(17.98±8.84)%]降低(P<0.01);动态平衡综合得分[(81.58±3.67)分]较对照组[(62.50±29.24)分]增高(P<0.01)。 结论:外周性前庭康复可以加速前庭代偿,对前庭神经炎是一种确实有效的治疗方法。.

Keywords: vertigo; vestibular neuritis; vestibular rehabilitation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Caloric Tests
  • Glucocorticoids* / therapeutic use
  • Humans
  • Methylprednisolone* / therapeutic use
  • Nystagmus, Pathologic*
  • Vestibular Neuronitis* / drug therapy
  • Vestibule, Labyrinth*

Substances

  • Glucocorticoids
  • Methylprednisolone