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Microb Drug Resist. 2019 Jun;25(5):677-680. doi: 10.1089/mdr.2018.0408.

Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India.

Author information

1
1 Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
2
2 Chan Zuckerberg Biohub, San Francisco, California.
3
3 Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, California.
4
4 Division of Pediatric Infectious Diseases and Global Health, Department of Pediatrics, University of California, San Francisco, San Francisco, California.
5
5 Hospital Epidemiology and Infection Control, University of California, San Francisco, San Francisco, California.
6
6 Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California.
7
7 Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California.

Abstract

Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India. We identified close phylogenetic relatedness to the South Asia clade and ERG11 Y132F and FKS1 S639Y mutations potentially explaining antifungal resistance.

KEYWORDS:

; antimicrobial resistance; echinocandin resistance; emerging infection; metagenomic

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