Format

Send to

Choose Destination
Clin Transplant. 2019 Jun 2:e13623. doi: 10.1111/ctr.13623. [Epub ahead of print]

Candida infections in solid organ transplantation: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

Author information

1
Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, California.
2
Multi-organ Transplant Program, Division of Infectious Diseases, Department of Medicine, University of Toronto, University Health Network, Toronto, Ontario, Canada.

Abstract

These updated guidelines from the American Society of Transplantation Infectious Diseases Community of Practice provide recommendations for the diagnosis and management of Candida infections in solid organ transplant recipients. Candida infections manifest primarily as candidemia and invasive candidiasis and cause considerable morbidity and mortality. Early diagnosis and initiation of treatment are necessary to reduce mortality. For both candidemia and invasive candidiasis, an echinocandin is recommended for initial therapy. However, early transition to oral therapy is encouraged when patients are stable and the organism is susceptible. Candida prophylaxis should be targeted for high-risk patients in liver, small bowel, and pancreas transplant recipients. Future research should address which patient groups may benefit most from preventative antifungal therapy strategies.

KEYWORDS:

antifungal; fungal; infection and infectious; infection and infectious agents

PMID:
31155770
DOI:
10.1111/ctr.13623

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center