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J Rheumatol Suppl. 2019 Jun;95:20-27. doi: 10.3899/jrheum.190114.

Cardiovascular Diseases in Psoriasis and Psoriatic Arthritis.

Author information

1
From the Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada; Laboratory of Inflammation and Cardiometabolic Diseases, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, Maryland, USA; Division of Dermatology and Venereology, Geneva University Hospitals, and Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland; Department of Rheumatology, Uppsala University Hospital, Uppsala, Sweden. Lihi.EDER@wchospital.ca.
2
L. Eder, MD, PhD, Women's College Research Institute, Women's College Hospital, University of Toronto; A. Dey, MD, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; A.A. Joshi, MD, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; W.H. Boehncke, MD, Professor and Chair, Division of Dermatology and Venereology, Geneva University Hospitals, and Department of Pathology and Immunology, University of Geneva; N.N. Mehta, MD, MSCE, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; A. Szentpetery, MD, PhD, Department of Rheumatology, Uppsala University Hospital. Lihi.EDER@wchospital.ca.
3
From the Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada; Laboratory of Inflammation and Cardiometabolic Diseases, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, Maryland, USA; Division of Dermatology and Venereology, Geneva University Hospitals, and Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland; Department of Rheumatology, Uppsala University Hospital, Uppsala, Sweden.
4
L. Eder, MD, PhD, Women's College Research Institute, Women's College Hospital, University of Toronto; A. Dey, MD, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; A.A. Joshi, MD, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; W.H. Boehncke, MD, Professor and Chair, Division of Dermatology and Venereology, Geneva University Hospitals, and Department of Pathology and Immunology, University of Geneva; N.N. Mehta, MD, MSCE, Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, NIH; A. Szentpetery, MD, PhD, Department of Rheumatology, Uppsala University Hospital.

Abstract

Patients with psoriatic disease have an increased risk of developing cardiovascular (CV) events. Recent advances in imaging and biomarker research provide insights into the underlying mechanisms that link these conditions. Here, we summarize recent work in this field that was presented at the July 2018 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) annual meeting in Toronto, Ontario, Canada. The presentations highlighted recent data about the association between psoriasis and vascular inflammation, the use of coronary angiogram to investigate CV outcomes, new approaches for CV risk stratification, and the shared pathomechanisms of psoriasis and atherosclerosis.

KEYWORDS:

CARDIOVASCULAR DISEASE; GRAPPA; MYOCARDIAL INFARCTION; PSORIASIS; PSORIATIC ARTHRITIS

PMID:
31154400
DOI:
10.3899/jrheum.190114

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