Dr. James Roberts has made seminal contributions to the understanding of the physiology of pregnancy, and, in particular, to the mechanisms of disease responsible for preeclampsia. His research includes endothelial cell dysfunction, oxidative stress, and other factors that play a role in the pathogenesis of preeclampsia; the use of antioxidant therapy to prevent the syndrome; identification of clinical subtypes of preeclampsia; and assessment of the long-term cardiovascular risk of the disorder. Dr. Roberts is currently an investigator at the Magee-Womens Research Institute and a Professor of Obstetrics, Gynecology, and Reproductive Sciences, Endocrinology, and Clinical and Translational Medicine at the University of Pittsburgh. He was the founding Director of the Magee-Womens Research Institute, and formerly the Elsie Hilliard Hillman Chair in Women’s and Infants’ Health Research at the University of Pittsburgh. For his many original contributions to the understanding of preeclampsia and other obstetrical syndromes, Dr. Roberts is herein recognized as a “Giant in Obstetrics and Gynecology.”