Format

Send to

Choose Destination
Mater Sci Eng C Mater Biol Appl. 2019 Sep;102:171-185. doi: 10.1016/j.msec.2019.04.051. Epub 2019 Apr 16.

Graphene and its derivatives: Opportunities and challenges in dentistry.

Author information

1
Marquette University School of Dentistry, Milwaukee, WI 53233, USA. Electronic address: mohammadreza.tahriri@marquette.edu.
2
Marquette University School of Dentistry, Milwaukee, WI 53233, USA.
3
Department of Materials Engineering, Imam Khomeini International University, Qazvin 34149-16818, Iran.
4
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore; Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, 138634, Singapore.
5
Marquette University School of Dentistry, Milwaukee, WI 53233, USA. Electronic address: lobat.tayebi@marquette.edu.

Abstract

The emerging science of graphene-based engineered nanomaterials as either nanomedicines or dental materials in dentistry is growing. Apart from its exceptional mechanical characteristics, electrical conductivity and thermal stability, graphene and its derivatives can be functionalized with several bioactive molecules, allowing them to be incorporated into and improve different scaffolds used in regenerative dentistry. This review presents state of the art graphene-based engineered nanomaterial applications to cells in the dental field, with a particular focus on the control of stem cells of dental origin. The interactions between graphene-based nanomaterials and cells of the immune system, along with the antibacterial activity of graphene nanomaterials are discussed. In the last section, we offer our perspectives on the various applications of graphene and its derivatives in association with titanium dental implants, membranes for bone regeneration, resins, cements and adhesives, as well as tooth-whitening procedures.

KEYWORDS:

Biocompatibility; Dentistry; Graphene; Graphene oxide; Stem cells; Tissue engineering

PMID:
31146988
DOI:
10.1016/j.msec.2019.04.051

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center