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Am J Infect Control. 2019 Jun;47S:A3-A9. doi: 10.1016/j.ajic.2019.01.018.

Disinfection, sterilization, and antisepsis: An overview.

Author information

1
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC. Electronic address: brutala@med.unc.edu.
2
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC; Department of Hospital Epidemiology, University of North Carolina Hospitals, Chapel Hill, NC.

Abstract

All invasive procedures involve contact by a medical device or surgical instrument with a patient's sterile tissue or mucous membranes. The level of disinfection or sterilization is dependent on the intended use of the object. Critical (items that contact sterile tissue, such as surgical instruments), semicritical (items that contact mucous membranes, such as endoscopes), and noncritical (devices that contact only intact skin, such as stethoscopes) items require sterilization, high-level disinfection, and low-level disinfection, respectively. Cleaning must always precede high-level disinfection and sterilization. Antiseptics are essential to infection prevention as part of a hand hygiene program, as well as other uses, such as surgical hand antisepsis and preoperative skin preparation.

KEYWORDS:

Antisepsis; Disinfection; Sterilization

PMID:
31146848
DOI:
10.1016/j.ajic.2019.01.018

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