Send to

Choose Destination
Asian J Neurosurg. 2019 Apr-Jun;14(2):392-398. doi: 10.4103/ajns.AJNS_299_18.

Impact of Comorbidities on Outcome Following Revision of Recurrent Single-Level Lumbar Disc Prolapse between Revision Microdiscectomy and Posterior Lumbar Interbody Fusion: A Single-Institutional Analysis.

Author information

Department of Surgery, Lagoon Hospitals, Lagos, Nigeria.
Department of Neurosurgery, Amrita Institute of Medical Sciences and Research, Kochi, Kerala, India.



Reports exist in the literature on the relationship between comorbid conditions and recurrence of lumbar disc herniation. Meanwhile, documented evidence abound on microdiscectomy and posterior lumbar interbody fusion (PLIF) as techniques of managing recurrent disc prolapse. Some surgeons would choose to perform PLIF instead of microdiscectomy for a first time re-herniation, because of the possibility of higher chances of further recurrence as well as increased likelihood of spinal instability following treatment with microdiscectomy. In this study, the authors sought to determine whether PLIF is better than microdiscectomy for first-time recurrent single-level lumbar disc prolapse and to compare the impact of comorbidities on outcome following revision.

Patients and Methods:

This was retrospective review of surgical treatment of patients with recurrent single-level disc prolapse with either microdiscectomy or PLIF at a tertiary health institution in India.


A total of 26 patients were evaluated. There was no statistically significant correlation between the presence of comorbidity and outcome in terms of improvement of pain (P > 0.05 at 95% degree of confidence; Spearman's ρ =0.239). Patients who had PLIF were neither more nor less likely to have a better outcome compared to those who had microdiscectomy, though this finding was not statistically significant (odds ratio = 0.263; P = 0.284).


There was no significant relationship between the presence of comorbidity and outcome following revision. Microdiscectomy did not prove to be a better option than PLIF for surgical management of recurrent single-level disc prolapse. A quality randomized controlled study would help to validate these findings.


Posterior lumbar interbody fusion; recurrent single-level disc prolapse; revision microdiscectomy; revision surgery

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center