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J Res Med Sci. 2019 Apr 26;24:38. doi: 10.4103/jrms.JRMS_437_18. eCollection 2019.

Medical imaging modalities using nanoprobes for cancer diagnosis: A literature review on recent findings.

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Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
School of Physics, University Sains Malaysia, Pulau Penang, Malaysia.
Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.


Medical imaging modalities are used for different types of cancer detection and diagnosis. Recently, there have been a lot of studies on developing novel nanoparticles as new medical imaging contrast agents for the early detection of cancer. The aim of this review article is to categorize the medical imaging modalities accompanying with using nanoparticles to improve potential imaging for cancer detection and hence valuable therapy in the future. Nowadays, nanoparticles are becoming potentially transformative tools for cancer detection for a wide range of imaging modalities, including computed tomography (CT), magnetic resonance imaging, single photon emission CT, positron emission tomography, ultrasound, and optical imaging. The study results seen in the recent literature provided and discussed the diagnostic performance of imaging modalities for cancer detections and their future directions. With knowledge of the correlation between the application of nanoparticles and medical imaging modalities and with the development of targeted contrast agents or nanoprobes, they may provide better cancer diagnosis in the future.


Cancer; diagnosis; medical imaging; nanoparticles

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