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Annu Rev Biochem. 1987;56:317-32.

Impact of virus infection on host cell protein synthesis.


There is good evidence that a variety of viruses encode functions that inhibit activation of either ribonuclease L or the Pl/eIF-2 alpha kinase. In general, this capability is evident among viruses that maintain long-term active or latent infections, and must therefore deal with interferon-induced antiviral responses of their hosts.

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