Interaction Between Ticagrelor and CYP3A4 Inhibitor: Importance of P2Y₁₂ Function Testing to Assess Platelet Recovery Before Surgery

J Cardiothorac Vasc Anesth. 2019 Nov;33(11):3221-3222. doi: 10.1053/j.jvca.2019.05.004. Epub 2019 May 10.

Authors

Marc Azran¹, Kenichi A Tanaka²

Affiliations

¹ Department of Anesthesiology, University of Maryland Baltimore Washington Medical Center, Glen Burnie, MD.
² Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD.

PMID: 31130316
DOI: 10.1053/j.jvca.2019.05.004

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Cardiac Surgical Procedures / adverse effects*
Cytochrome P-450 CYP3A Inhibitors / adverse effects*
Drug Interactions
Humans
Male
Platelet Aggregation / drug effects*
Postoperative Hemorrhage / chemically induced*
Purinergic P2Y Receptor Antagonists / adverse effects
ST Elevation Myocardial Infarction / blood
ST Elevation Myocardial Infarction / therapy*
Ticagrelor / adverse effects*

Substances

Cytochrome P-450 CYP3A Inhibitors
Purinergic P2Y Receptor Antagonists
Ticagrelor