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Med Sci (Paris). 2019 May;35(5):483-485. doi: 10.1051/medsci/2019080. Epub 2019 May 22.

[Hachimoji DNA extends coding possibilities].

[Article in French]

Author information

1
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS ; CoReBio PACA, case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France.

Abstract

The synthesis of four new nucleotide analogues that can form hydrogen bonds within the DNA double helix and can be incorporated without distortion of the structure extends the possibilities of synthetic biology. Although functional use of these analogues remains in the future, they already have interesting applications and represent an important step forward.

PMID:
31115333
DOI:
10.1051/medsci/2019080

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