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Molecules. 2019 May 16;24(10). pii: E1888. doi: 10.3390/molecules24101888.

A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus.

Author information

1
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. cwh18363032223@163.com.
2
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. 18363036656@163.com.
3
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. cleanlq@163.com.
4
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. 13465150376@163.com.
5
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. zhongyiyao77@126.com.
6
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. liuyuhongwu@126.com.
7
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. xulingchuan518@sina.com.
8
Key Laboratory of Medicinal Fungi and Resource Development in Shandong Province, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. xulingchuan518@sina.com.

Abstract

Phellinus linteus is a popular medicinal mushroom that is widely used in China, Korea, Japan, and other Asian countries. P. linteus comprises various bioactive components, such as polysaccharides, triterpenoids, phenylpropanoids, and furans, and has proven to be an effective therapeutic agent in traditional Chinese medicine for the treatment and the prevention of various diseases. A number of studies have reported that P. linteus possesses many biological activities useful for pharmacological applications, including anticancer, anti-inflammatory, immunomodulatory, antioxidative, and antifungal activities, as well as antidiabetic, hepatoprotective, and neuroprotective effects. This review article briefly presents the recent progress made in understanding the bioactive components, biological activities, pharmacological applications, safety, and prospects of P. linteus, and provides helpful references and promising directions for further studies of P. linteus.

KEYWORDS:

Phellinus linteus; biological activities; pharmacological applications; polyphenols; polysaccharides

PMID:
31100959
PMCID:
PMC6572527
DOI:
10.3390/molecules24101888
[Indexed for MEDLINE]
Free PMC Article

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