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J Clin Med. 2019 May 16;8(5). pii: E690. doi: 10.3390/jcm8050690.

Pretransplant Cardiac Evaluation Using Novel Technology.

Author information

1
Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA. mohamad_r_hemu@rush.edu.
2
Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA. Allison_C_Zimmerman@rush.edu.
3
Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA. Dinesh_Kalra@rush.edu.
4
Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA. tokwuosa@rush.edu.

Abstract

Hematopoietic stem-cell transplantation (HSCT) is a complex procedure that has been increasingly successful in treating malignant and nonmalignant conditions. Despite its effectiveness, it can be associated with potentially life-threatening adverse effects. New onset heart failure, ischemic disease, and arrhythmias are among the most notable cardiovascular complications post-HSCT. As a result, appropriate cardiac risk stratification prior to transplant could result in decreased morbidity and mortality by identifying patients with a higher probability of tolerating possible toxicities associated with HSCT. In this review, we aim to discuss the utility of cardiac screening using novel modalities of imaging technology in the pre-HSCT phase.

KEYWORDS:

cardiac imaging; cardiac magnetic resonance; cardiovascular complications; coronary computed tomography; echocardiogram; hematopoietic stem cell transplant; speckle tracking echocardiography

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