Send to

Choose Destination
J Int Med Res. 2019 Jun;47(6):2647-2654. doi: 10.1177/0300060519845780. Epub 2019 May 17.

Prediction of the induction to delivery time interval in vaginal dinoprostone-induced labor: a retrospective study in a Chinese tertiary maternity hospital.

Author information

Department of Obstetrics, Maternity and Child Health Hospital of Hubei Province, Hongshan District, Wuhan, China.



This study aimed to investigate the potential factors that affect the induction to delivery time interval in women undergoing induction of labor with a controlled-release dinoprostone vaginal insert.


Pregnant women who presented for delivery at Hubei Maternal and Child Health Hospital from January 2016 to August 2016 were recruited. Finally, 1265 women who underwent labor induction with a vaginal dinoprostone (PGE2) insert were analyzed. Univariate and multivariate linear regression analyses were used to estimate the relevant risks for delivery time.


Among the1265 subjects, the mean delivery time was 18.92 ± 12.50 hours. Univariate and multivariate analyses showed that fetal weight, an obstetric complication (premature rupture of the membranes), and the delivery history were significantly associated with the induction to delivery time. Biparietal diameter was related to the vaginal delivery time in univariate analysis, but there was no significant difference after adjustment in multivariate analysis.


Vaginal dinoprostone is an effective method for successful induction of labor. Gestational age, parity, and fetal weight are major factors that predict the induction to delivery time interval.


Cervical ripening; dinoprostone; fetal weight; gestational age; induction; labor; vaginal delivery time

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center