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Adv Nutr. 2019 May 1;10(suppl_2):S154-S163. doi: 10.1093/advances/nmy107.

Effects of Milk and Dairy Product Consumption on Type 2 Diabetes: Overview of Systematic Reviews and Meta-Analyses.

Author information

1
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain.
2
Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile.
3
Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA.
4
Department of Food Sciences and Nutrition, School of Applied Health Sciences and Wellness.
5
Diabetes Institute, Ohio University, Athens, OH.
6
PROFITH (PROmoting FITness and Health through Physical Activity) Research Group, Department of Physical Education and Sport, Faculty of Sport Sciences.
7
Department of Biochemistry and Molecular Biology II, School of Pharmacy.
8
Institute of Nutrition and Food Technology "José Mataix," Biomedical Research Center, University of Granada, Granada, Spain.
9
Instituto de Investigación Biosanitaria ibs GRANADA, Complejo Hospitalario Universitario de Granada, Granada, Spain.
10
CIBEROBN (CIBER Physiopathology of Obesity and Nutrition CB12/03/30028), Instituto de Salud Carlos III, Madrid, Spain.

Abstract

Dairy product consumption has been related to type 2 diabetes (T2D) incidence, although data from epidemiological studies have shown mixed results regarding the association of dairy products and T2D risk. This overview of systematic reviews and meta-analyses aimed to examine the scientific literature available on the association between dairy product consumption and T2D risk. A literature search was conducted in the MEDLINE (via PubMed), EMBASE, Cochrane Central Database of Systematic Reviews, and Web of Science databases from their inception to April, 2018. Forest plots summarized the risk ratios (RRs) reported by meta-analyses on high compared with low and dose-response dairy product consumption. The risk of bias was assessed using the AMSTAR2 tool. We included 12 meta-analyses, reporting data from 4-22 cohort studies and from 4-23 populations. The participants' ages ranged from 20 to 88 y, and participants were followed up for from 4 to 30 y. Studies included 64,227-566,875 participants and reported 4810-44,474 cases of T2D. Most studies reported an inverse association between T2D incidence and dairy product consumption, especially for 1) total dairy products (range: 0.86-0.91), 2) low-fat dairy products (range: 0.81-0.83), 3) low-fat milk (RR: 0.82), and 4) yogurt (range: 0.74-0.86). Dose-response analyses showed a decreased T2D risk for 1) 200-400 g/d of total dairy products (range: 0.93-0.97) and 2) 200 g/d of low-fat dairy products (range: 0.88-0.91). Total dairy product consumption is associated with a lower risk of T2D, especially for yogurt and low-fat dairy consumption. The association with cheese is moderate. Moreover, dose-response analyses showed that the risk of T2D decreased by each unit increase in consumption of total dairy products and low-fat dairy products.

KEYWORDS:

cheese; dairy products; diabetes mellitus; meta-analysis; milk; review; type 2 diabetes; yogurt

PMID:
31089734
PMCID:
PMC6518137
[Available on 2020-05-01]
DOI:
10.1093/advances/nmy107

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