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Medicine (Baltimore). 2019 May;98(19):e15551. doi: 10.1097/MD.0000000000015551.

A case report on the acute and late complications associated with carbon monoxide poisoning: Acute kidney injury, rhabdomyolysis, and delayed leukoencephalopathy.

Author information

1
Department of Internal Medicine, Catholic University of Daegu School of Medicine.
2
Department of Psychiatry, School of Medicine, Kyungpook National University, Daegu, Korea.

Abstract

RATIONALE:

Acute kidney injury (AKI), rhabdomyolysis, and delayed leukoencephalopathy after carbon monoxide (CO) poisoning are very rare. We report a case presenting with AKI, rhabdomyolysis, and delayed leukoencephalopathy after CO poisoning.

PATIENT CONCERNS:

The patient was admitted to our emergency department due to loss of consciousness after CO exposure during a suicide attempt.

DIAGNOSES:

Laboratory findings revealed elevated carboxyhemoglobin, serum creatinine, and serum muscle enzyme levels. Initially, this patient was diagnosed with AKI and rhabdomyolysis due to CO poisoning. A month after the CO poisoning, she showed neuropsychiatric symptoms. Brain magnetic resonance imaging showed white-matter hyperintensity on the T2 flair image. Therefore, she was diagnosed with delayed leukoencephalopathy after CO poisoning.

INTERVENTIONS:

At the same time as diagnosis of AKI and rhabdomyolysis, the normobaric oxygen and hydration therapies were performed. A month later, rehabilitation was started due to delayed leukoencephalopathy.

OUTCOMES:

Her renal function and muscle enzyme levels were completely restored with alert mental status. She could walk with the aid of a walker at last visit.

LESSONS:

This case shows that we should consider about rare acute and late complications such as AKI, rhabdomyolysis, and delayed leukoencephalopathy after CO poisoning.

PMID:
31083215
PMCID:
PMC6531082
DOI:
10.1097/MD.0000000000015551
[Indexed for MEDLINE]
Free PMC Article

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