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Neuron. 2019 May 8;102(3):509-511. doi: 10.1016/j.neuron.2019.04.025.

Nuclear Pore Complexes Are Key Regulators of Oligodendrocyte Differentiation and Function.

Author information

1
Development, Aging and Regeneration Program and NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
2
Development, Aging and Regeneration Program and NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. Electronic address: mdangelo@sbpdiscovery.org.

Abstract

Increasing evidence points to nuclear pore complexes as important regulators of cell fate and tissue homeostasis. A recent report by Liu et al. (2019) in this issue of Neuron uncovers that nucleoporin Seh1 is required for the expression of genes critical for oligodendrocyte differentiation and myelination.

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