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Arch Osteoporos. 2019 May 8;14(1):51. doi: 10.1007/s11657-019-0603-4.

Primary screening for increased fracture risk by the FRAX® questionnaire-uptake rates in relation to invitation method.

Author information

1
Department of Obstetrics and Gynaecology, Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-221 85, Lund, Sweden. louise.moberg@med.lu.se.
2
Department of Internal Medicine, Department of Clinical Sciences, Skåne University Hospital, Lund University, Malmö, Sweden.
3
Department of Orthopaedics, Department of Clinical Sciences Malmö, Skåne University Hospital, Lund University, Malmö, Sweden.
4
Department of Obstetrics and Gynaecology, Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-221 85, Lund, Sweden.

Abstract

The aim of the study was to evaluate the feasibility and most efficient way of offering middle-aged Swedish women a primary fracture screening program via a questionnaire. Two out of five invited women returned the FRAX questionnaire and those contacted directly by mail were most prone to respond.

PURPOSE:

Osteoporosis and its associated fractures are increasing, and this study aims to explore ways to identify women at an increased risk of fracture using the FRAX® algorithm.

METHODS:

Three thousand middle-aged women were invited and presented a questionnaire distributed by three different methods-by mail, at routine mammography, or internet-based.

RESULTS:

In total, 1120 (37.3%) women responded to the questionnaire and agreed to participate. The response rates for the mail, mammography, and internet-based groups were 39.1%, 35.7%, and 25.2% respectively. Women in the mammography group weighed more, were slightly older than the other women, and also had a higher BMI than women from the mail and internet-based groups. No difference was observed between the groups regarding previous fracture, family history for fracture, current smoking, glucocorticoid use, and alcohol usage. The mammography group had a higher median (interquartile range) major osteoporotic FRAX® score (10.0% (7.8-17.0)) than the mail group (9.7% (7.1-15.0); p = 0.005) and the internet-based group (8.7% (6.7-14.0); p = 0.001).

CONCLUSIONS:

Two out of five early postmenopausal women returned the questionnaire and women contacted directly by mail were more prone to respond. Out of the participants, 26.6% had a 10-year fracture risk score ≥ 15% according to the FRAX® algorithm.

KEYWORDS:

FRAX; Fracture risk; Screening; Women

PMID:
31069544
DOI:
10.1007/s11657-019-0603-4

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